Department of Applied Chemistry, Graduate School of Engineering, Osaka University
Akira ONODA Ph.D.
Akira ONODAPh.D. in Macromolecular Science
- Affiliation
Department of Applied Chemistry, Graduate School of Engineering, Osaka University
- Address
Room C4-623, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan
- Contact
E-mail: onoda[at]chem.eng.osaka-u.ac.jp ([at] = @)
Phone: +81-(0)6-6879-7929 Fax: +81-(0)6-6879-7930
Career
- DATE OF BIRTH
1/27/1975
- EDUCATION
Osaka University Ph.D. in Macromolecular Science 3/2002
Dissertation Title; Metal-Oxygen Bond Regulation by
Rearrangement of Hydrogen Bonding Networks
Osaka University M.S. in Macromolecular Science 3/1999
Osaka University B.S. in Macromolecular Science 3/1997- PROFESSIONAL EXPERIENCE
Associate Professor
Department of Applied Chemistry, Graduate School of Engineering, 4/2013–present
Osaka UniversityAssistant Professor
Frontier Research Base for Global Young Researchers, 4/2008–3/2013
Graduate School of Engineering,
Osaka UniversityDepartment of Applied Chemistry, Graduate School of Engineering, 4/2008–3/2013
Osaka UniversityResearch Associate 4/2007–3/2008
JSPS (Japan Society of the Promotion of Science) fellow Abroad
Departments of Molecular Biology and Chemistry,
The Scripps Research InstituteAssistant Professor 4/2003–3/2007
Department of Chemistry, Faculty of Science
Tokyo University of SciencePostdoctoral Research Fellow 4/2002–3/2003
JSPS (Japan Society of the Promotion of Science) fellow (PD)
Department of Earth and Space Science, Graduate School of Science
Osaka UniversityJSPS (Japan Society of the Promotion of Science) fellow (DC1) 4/1999–3/2002
Department of Macromolecular Science, Graduate School of Science
Osaka University
Activities
- Awards
1st Incentive Award of Japan Association of Chemical Innovation, 2012
Chancellor’s Incentive Award from Osaka University, 2013
Chancellor’s Incentive Award from Osaka University, 2014
Research Interests
Bioinorganic Chemistry, Metalloprotein Engineering, Nanobiotechnology, Macromolecular Science, Chemical Biology,
Selected Papers
- PUBLICATIONS
1.“Myoglobin-Based Non-Precious Metal Carbon Catalysts for an Oxygen Reduction Reaction”A. Onoda,* Y. Tanaka, T. Ono, S. Takeuchi, A. Sakai, T. Hayashi,*
J. Porphyr. Pthalocyanins, in press. (2015).2. “Artificial Hydrogenase: Biomimetic Approaches Controlling Active Molecular Catalysts”
A. Onoda,* Hayashi,*
Curr. Opin. Chem. Biol., 25, 133–140. (2015).3. “Generation of New Artificial Metalloproteins by Cofactor Modification of Native Hemoproteins”
T. Hayashi,* A. Onoda, Y. Sano
Israel J. Chem., 55, 76–84. (2015).4. “Enzyme-substrate complex structures of CYP154C5 shed light on its mode of highly selective steroid hydroxylation”
K. Herzog, P. Bracco, A. Onoda, T. Hayashi, K. Hoffmann, A. Schallmey
Acta Crystallogr. Sect. D., 2875–2889. (2014).5. “Photoinduced Hydrogen Evolution Catalyzed by a Synthetic Diiron Dithiolate Complex Embedded within a Protein Matrix”
A. Onoda,* Y. Kihara, K. Fukumoto, Y. Sano, T. Hayashi*
ACS Catal., 4, 2645–2648 (2014).6. “Photochemical Property of Myoglobin−CdTe Quantum Dot Conjugate Formed by Supramolecular Host−guest Interaction”
T. Himiyama, A. Onoda,* T. Hayashi*
Chem. Lett., 43, 1152–1154 (2014).7. “Fabrication of enzyme-degradable and size-controlled protein nanowires using single particle nano-fabrication technique”
M. Omichi, A. Asano, S. Tsukuda, K. Takano, M. Sugimoto, A. Saeki, D. Sakamaki, A. Onoda, T. Hayashi, S. Seki*
Nature Commun., 5, 3718 (2014).8. “A Rhodium Complex-linked Hybrid Biocatalyst: Stereo-controlled Phenylacetylene Polymerization within an Engineered Protein Cavity”
K. Fukumoto, A. Onoda, E. Mizohata, M. Bocola, T. Inoue, U. Schwaneberg, T. Hayashi*
ChemCatChem., 6, 1229–1235 (2014). Front Cover.9. “H2O2-dependent Substrate Oxidation by an Engineered Diiron Site in a Bacterial Hemerythrin”
Y. Okamoto, A. Onoda,* H. Sugimoto, Y. Takano, S. Hirota, D. M. Kurtz, Jr., Y. Shiro, T. Hayashi*
Chem. Commun., 50, 3421−3423 (2014). Front Cover.10. “Crystal Structure, Exogenous Ligand Binding and Redox Properties of an Engineered Diiron Active Site in a Bacterial Hemerythrin”
Y. Okamoto, A. Onoda,* H. Sugimoto, Y. Takano, S. Hirota, D. M. Kurtz, Jr., Y. Shiro, T. Hayashi*
Inorg. Chem., 52, 13014−13020 (2013).11. “Cathodic Photocurrent Generation from Zinc-substituted Cytochrome b562 Assemblies Immobilized on an Apocytochrome b562-modified Gold Electrode”
A. Onoda,* Y. Kakikura, T. Hayashi*
Dalton Trans., 42, 16102−16107 (2013).12. “Supramolecular Linear Assemblies of Cytochrome b562 Immobilized on a Gold Electrode”
Y. Kakikura, A. Onoda,* E. Kubo, H. Kitagishi, T. Uematsu, S. Kuwabata, T. Hayashi*
J. Inorg. Organomet. Polym. Mater., 23, 172−179 (2013).13. " Supramolecular Assembling Systems Formed by Heme–heme Pocket Interactions in Hemoproteins"
K. Oohora, A. Onoda, T. Hayashi
Chem. Commun., 48, 11714–11726 (2012).14. “Photocurrent Generation of Hierarchical Zinc-substituted Hemoprotein Assemblies Immobilized on a Gold Electrode”
A. Onoda, Y. Kakikura, T. Uematsu, S. Kuwabata, T. Hayashi
Angew. Chem. Int. Ed., 51,2628–2631 (2012). Hot Paper.15. "Chemically Programmed Supramolecular Assembly of Hemoprotein and Streptavidin with Alternating Alignment"
K. Oohora, S. Burazerovic, A. Onoda, Y. M. Wilson, T. R. Ward, T. Hayashi
Angew. Chem. Int. Ed., 51, 3818-3821 (2012). Front Cover.16. "A Rhodium Complex-Linked b-Barrel Protein as a Hybrid Biocatalyst for Phenylacetylene Polymerization"
A. Onoda, K. Fukumoto, M. Arlt, M. Bocola, U. Schwaneberg, T. Hayashi
Chem. Commun., 48, 9756–9758 (2012).17. “Photochemical properties of a myoglobin–CdTe quantum dot conjugate”
A. Onoda, T. Himiyama, K. Ohkubo, S. Fukuzumi, T. Hayashi
Chem. Commun., 48, 8054–8056 (2012). Inside Front Cover.18. “Fibrous Supramolecular Hemoprotein Assemblies Connected with Synthetic Heme Dimer and Apohemoprotein Dimer”
A. Onoda, A. Takahashi, K. Oohora, Y. Onuma, T. Hayashi
Chemistry & Biodiversity, 9. 1689–1692 (2012).19. “Photocatalytic Hydrogen Evolution by a Diiron Hydrogenase Model Based on a Peptide Fragment of Cytochrome c556 with an Attached Diiron Carbonyl Cluster and an Attached Ruthenium Photosensitizer”
Y. Sano, A. Onoda, T. Hayashi
J. Inorg. Biochem., 105, 159–162 (2012).20. “Crystal Structure and Spectroscopic Studies of a Stable Mixed-Valent State of the Hemerythrin-like Domain of a Bacterial Chemotaxis Protein”
A. Onoda, Y. Okamoto, H. Sugimoto, Y. Shiro, T. Hayashi
Inorg. Chem., 50, 4892–4899 (2011).21. “A Hydrogenase Model System Based on the Sequence of Cytochrome c: Photochemical Hydrogen Evolution in Aqueous Media”
Y. Sano, A. Onoda, T. Hayashi
Chem. Commun., 8229 –8231 (2011). Inside Front Cover.22. “A Chemically-controlled Supramolecular Protein Polymer Formed by a Myoglobin-based Self-assembly System”
K. Oohora, A. Onoda, H. Kitagishi, H. Yamaguchi, A. Harada, T. Hayashi
Chem. Sci., 2, 1033–1038 (2011). Backside Cover.23. “Preparation and Reactivity of a Tetranuclear Fe(II) Core in the Metallothionein a-Domain”
Y. Sano, A. Onoda, R. Sakurai, H. Kitagishi, T. Hayashi
J. Inorg. Biochem., 105, 702–708 (2011).24. “Supramolecular Hemoprotein–Gold Nanoparticle Conjugates”
A. Onoda, Y. Ueya, T. Sakamoto, T. Uematsu, T. Hayashi
Chem. Commun., 9107–9109 (2010). Front Cover.25. “DNA-binding Hemoproteins Tethering Polyamine Interface”
A. Onoda, H. Nagai, S. Koga, T. Hayashi
Bull . Chem. Soc. Jpn., 83, 375–377 (2010).26. “Supramolecular Protein–Protein Complexation via Specific Interaction Between Glycosylated Myoglobin and Sugar-binding Protein”
H. Nagai, A. Onoda, T. Matsuo, T. Hayashi
Supramol. Chem., 22, 57–64 (2010).27. “Alignment of Gold Clusters on DNA via a DNA-recognizing Zinc Finger-Metallothionein Fusion Protein”
S. Ariyasu, A. Onoda, R. Sakamoto, T. Yamamura
Bioconjugate Chem., 20 , 2278–2285 (2009).28. “Minimal Motif Peptide Structure of Metzincin Clan Zinc Peptidases in Micelles”
A. Onoda, T. Suzuki, H. Ishizuka, R. Sugiyama, S. Ariyasu, T. Yamamura
J. Pep. Sci., 15, 832–841 (2009).29. “Porphyrin Arrays Responsive to Additives. Fluorescence Tuning”
T. Yamamura, S. Suzuki, T. Taguchi, A. Onoda, T. Kamachi, I. Okura
J. Am. Chem. Soc., 131, 11719–11726 (2009).30. “Circular Dichroism of Neutral Zinc Porphyrin-Oligonucleotide Conjugates Modified with Flexible Linker”
A. Onoda, M. Igarashi, S. Naganawa, K. Sasaki, S. Ariyasu, T. Yamamura
Bull. Chem. Soc. Jpn., 82, 12880–1286 (2009).31. “Conjugation of Au11 Cluster with Cys-rich Peptides Containing the a-domain of Metallothionein”
S. Ariyasu, A. Onoda, R. Sakamoto, T. Yamamura
Dalton Trans., 21, 3742–3747 (2009).32. “Inorganic-Organic Calcium Carbonate Composite of Synthetic Polymer Ligands with an Intramolecular NH···O Hydrogen Bonds”
N. Ueyama, K. Takahashi, A. Onoda, T. Okamura, H. Yamamoto
Top. Curr. Chem., 271, 155–193 (2007).33. “Photoinduced Switching of Intramolecular Hydrogen Bond between Amide NH and Carboxyl Oxygen”
T. Matsuhira, H. Yamamoto, A. Onoda, T. Okamura, N. Ueyama
Org. Biomol. Chem., 4, 1338–1342 (2006).34. “Calcium Ion Responsive DNA Binding in Zinc Finger Fusion Protein”
A. Onoda, N. Arai, N. Shimazu, H. Yamamoto, T. Yamamura
J. Am. Chem. Soc., 127, 16535–16540 (2005).35. “Covalent Immobilization of Metal-binding Motifs of Enzymes on Quartz Surface. [Ni(Cys-X2-Cys)2]2– of Hydrogenases.”
D. Sakaniwa, T. Ohe, T. Misumi, H. Monjushiro, A. Onoda, T. Yamamura
Chem. Lett. 34, 1634–1635 (2005).36. “Switching of Turn Conformation in an Aspartate Anion Peptide Fragment by NH···O Hydrogen Bonds”
A. Onoda, H. Yamamoto, Y. Yamada, K. Lee, S. Adachi, T. Okamura, K.-Y. Kumagaye, K. Nakajima, T. Kawakami, S. Aimoto, N. Ueyama
Biopolymers (Peptide Science), 80, 233–248 (2005).37. “Proton-Driven Conformational Switch of Cyclohexyl Skeleton Coupling with NH···O Hydrogen Bond Formation”
A. Onoda, H. Haruna, H. Yamamoto, K. Takahashi, H. Kozuki, T. Okamura, N. Ueyama
Eur. J. Org. Chem., 641–645 (2005).38. “Structures and properties of octaethylporphinato(phenolate)iron(III) complexes with NH···O hydrogen bonds: modulation of Fe–O bond character by the hydrogen bond”
D. Kanamori, Y. Yamada, A. Onoda, T. Okamura, S. Adachi, H. Yamamoto, N. Ueyama
Inorg. Chim. Acta., 358, 331–338 (2005).39. “catena-Poly[[triaquabis(2,6-diacetamido-benzoato)terbium(III)]-l-2,6-diacetamido-benzoato] monohydrate]”
A. Onoda, T. Okamura, H. Yamamoto, N. Ueyama
Acta Crystallogr. E, E60, m1196–m1198 (2004).40. “Stabilization of Calcium- and Terbium-Carboxylate Bonds by NH···O Hydrogen Bonds in Mononuclear Complex: A Functional Model of the Active Site of Calcium Binding Proteins”
A. Onoda, Y. Yamada, Y. Nakayama, H. Adachi, T. Okamura, A. Nakamura, H. Yamamoto, N. Ueyama, D. Vyprachticky, Y. Okamoto
Inorg. Chem., 43, 4447–4455 (2004).41. “Highly Oriented Aragonite Nanocrystal-biopolymer Composites in an Aragonite Brick of the Nacreous Layer of Pinctada fucata.”
K. Takahashi, H. Yamamoto, A. Onoda, M. Doi, T. Inaba, M. Chiba, A. Kobayashi, T. Taguchi, T. Okamura, N. Ueyama
Chem. Comm., 996–997 (2004).42. “Stabilization of Carboxylate Anion with NH···O Hydrogen Bond: Facilitation of the Deprotonation of Carboxylic Acid by the Neighboring Amide NH Groups”
A. Onoda, Y. Yamada, J. Takeda, Y. Nakayama, T. Okamura, M. Doi, H. Yamamoto, N. Ueyama
Bull. Chem. Soc. Jpn., 77, 321–329 (2004).43. “Solid State 31P MAS NMR Detection of Hydrogen-Bonded Phosphate Polymer in Calcium-Phosphate Composites”
A. Onoda, M. Doi, K. Takahashi, T. Okamura, H. Yamamoto, H. Ueyama
Chem. Lett. 33, 466–467 (2004).44. “Formation of 6-, 7- or 8- membered ring intra-side-chain NH···O hydrogen bond toward Ca-binding”
K. Takahashi, M. Doi, A. Kobayashi, T. Taguchi, A. Onoda, T. Okamura, H. Yamamoto, N. Ueyama
J. Crystal Growth, 263, 552–563 (2004).45. “Direct Observation of Polymer-Binding Site on Calcite Crystal by FE/SEM: Regulation of Binding Abilities by a Rotation of Amide Group in Poly(carboxylate) to CaCO3 Crystals”
K. Takahashi, M. Doi, A. Kobayashi, T. Taguchi, A. Onoda, T. Okamura, H. Yamamoto, N. Ueyama
Chem. Lett. 33, 192–193 (2004).46. “2,6-Bis(triphenylacetylamino)phenol”
A. Onoda, T. Okamura, H. Yamamoto, N. Ueyama
Acta Crystallogr. E, E59, o1205–o1207 (2003).47. “Distorted square planar Pd(II) complex with shortened Pd---Cl bond induced by bulky terpyridyl ligand, 6,6"-dimesityl-2,2':6',2"-terpyridine”
A. Onoda, K. Kawakita, T. Okamura, T. Yamamoto, N. Ueyama
Acta Crystallogr. E, E59, m291–m293 (2003).48. “(Acetonitrile)(6,6"-dimesityl-2,2':6',2"-terpyridine) copper(I) hexafluorophosphate”
A. Onoda, K. Kawakita, T. Okamura, T. Yamamoto, N. Ueyama
Acta Crystallogr. E, E59, m266–m267 (2003).49. “Synthesis of Zigzag-Chain and Cyclic-Octanuclear Calcium Complexes and Hexanuclear Bulky Aryl-Phosphate Sodium Complexes with Ortho-Amide Groups: Structural Transformation Involving a Network of Inter- and Intramolecular Hydrogen Bonds”
A. Onoda, Y. Yamada, T. Okamura, M. Doi, H. Yamamoto, N. Ueyama
J. Am. Chem. Soc. 124, 1052–1059 (2002).50. “Zigzag-Chain, Cyclic-Octanuclear Calcium- and Hexanuclear Sodium Phosphate Complexes with Bulky Amide Ligands Involving a Network of Inter- and Intramolecular Hydrogen Bonds”
A. Onoda, T. Okamura, H. Yamamoto, N. Ueyama
Molecular Crystals and Liquid Crystals. 379, 401–406 (2002).51. “Tight Binding of Poly(carboxylate) Ligand to Calcium Carbonate with Intramolecular NH···O Hydrogen Bond”
N. Ueyama, K. Takahashi, A. Onoda, T. Okamura, H. Yamamoto
Macromol. Symp. 186, 129–134.(2002).52. “Mononuclear Ca(II)-Bulky Aryl-Phosphate Monoanion and Dianion Complexes with Ortho-Amide Groups”
A. Onoda, Y. Yamada, T. Okamura, H. Yamamoto, N. Ueyama
Inorg. Chem., 41, 6038–6047 (2002).53. “Ca-O binding of poly[1-carboxylate-2-(N-t-butylcarbamoyl)ethylene-alt-ethylene] and calcium carbonate composites”
K. Takahashi, H. Kozuki, A. Onoda, T. Okamura, H. Yamamoto, N. Ueyama
J. Inorg. Organomet. Polym., 12, 99–108 (2002).54. “One-dimensional P–OH···O=P hydrogen bonds restricted by the bulky ligand, 2,6-diisopropylbenzene dihydrogen phosphate”
A. Onoda, Y. Okamura, H. Yamamoto, N. Ueyama
Acta Crystallogr. E. 57, o1022–o1024 (2001).55. “Secure Binding of Alternately Amidated Poly(acrylate) to Crystalline Calcium Carbonate by NH···O Hydrogen Bond”
N. Ueyama, H. Kozuki, M. Doi, Y. Yamada, K. Takahashi, A. Onoda, Y. Okamura, H. Yamamoto
Macromolecules, 34, 2607¬2614 (2001).56. “Dinuclear Calcium Complex with Weakly NH···O Hydrogen-bonded Sulfonate Ligands”
A. Onoda, Y. Yamada, M. Doi, T. Okamura, N. Ueyama
Inorg. Chem. 40, 516–521 (2001).57. “Protection of Proton-initiated Ligand Dissociation from Hg(II) Complexes with Bulky Amide Arenethiolate by NH···S Hydrogen Bonds in an Aqueous Micellar Solution”
N. Ueyama, M. Inohara, A. Onoda, T. Ueno, T. Okamura, A. Nakayama
Inorg. Chem. 38, 4028–4031 (1998).58. “Dinuclear Calcium Complexes with Intramolecularly NH···O Hydrogen-Bonded Dicarboxylate Ligand”
N. Ueyama, J. Takeda, Y. Yamada, A. Onoda, T. Okamura, A. Nakamura
Inorg. Chem., 38, 475–478 (1998).- INVITED LECTURES
1. “Linear Hemoprotein Assemblies on a Gold Surface”
A. Onoda
International Conference on Porphyrins and Phthalocyanins,
Istanbul, 27/7/2014.2. “Hemoprotein-based Hybrid Materials as Bioelectronic Interface”
A. Onoda
International Symposium on Polymeric Materials Based on Element-blocks,
Kyoto Institute of Technology, Kyoto, 31/5/2014.3. “Programmed Hemoprotein Assemblies as a Bioelectronic Interface”
A. Onoda
Asian International Meeting in the 94th Annual Meeting, The Chemical Society of Japan,
Nagoya University, Nagoya, 29/3/2014.4. “Programmed Hierarchical Assemblies of Hemoproteins as Bioelectronic Interface”
A. Onoda
International Symposium of Coordination Programming,
University of Tokyo, Tokyo, 21/1/2014.5. “Programmed Hemoprotein Assemblies as Surface Nanoarchitecture of Biodevices”
A. Onoda
Symposium on Chemistry of Coordination Architecture in
the 63th Conference of Japan Society of Coordination Chemistry,
University of the Ryukyus, Naha, 02/11/2013.6. “Programmed Hierarchical Assemblies of Hemoproteins toward Functional Biodevices”
A. Onoda
Japan-China Joint Coordination Chemistry Symposium for Young Scientists on
Advanced Coordination Materials,
Institute of Molecular Science, Okazaki, 15/06/2013.7.“Programmed Hemoprotein Assemblies as a Bioelectronic Interface”
A. Onoda
Japan-Taiwan Bilateral Workshop on Nano Science 2012,
Osaka University, Osaka, 05/12/2012.8.“Programmed Hemoprotein Assemblies toward Biodevices”
A. Onoda, T. Hayashi
The First International Symposium on Biofunctional Chemistry (ISBC2012),
Tokyo Institute of Technology, Tokyo, 27/11/2012.9. “Programmed Hierarchical Assemblies of Hemoproteins toward Functional Biodevices”
A. Onoda, T. Hayashi
Germany-Japan Bilateral Meeting on Coordination Programming, Tokyo, 25/10/2012.10. “Programmed Hemoprotein Assemblies on Metal Surfaces”
A. Onoda, Y. Ueya, Y. Kakikura, T. Himiyama, T. Hayashi
Asian Conference on Coordination Chemistry, Dehli, India, 17/10/2011.11. “Artificial Hemoprotein Assemblies Conjugated with Gold Surfaces”
A. Onoda, Y. Ueya, Y. Kakikura, A. Takahashi, K. Oohora, T. Hayashi
60th Anniversary Conference on Coordination Chemistry, Osaka, 28/9/2010.- Books
1. “Artificial Metalloenzymes Containing an Organometallic Active Site”
A. Onoda, T. Hayashi, M. Salmain
In Bioorganometallic Chemistry: Applications in Drug Discovery, Biocatalysis, and Imaging.,
Wiley-VCH, 2014.