共同研究先:
Prof. Ulrich Schwaneberg (RWTH Aachen University, Germany)
ホームページ:
https://www.biotec.rwth-aachen.de/
共同研究論文:
1. “Artificial Diels–Alderase based on the transmembrane protein FhuA”
Hassan Osseili, Daniel F. Sauer, Klaus Beckerle, Marcus Arlt, Tomoki Himiyama, Tino Polen, Akira Onoda, Ulrich Schwaneberg, Takashi Hayashi, and Jun Okuda
Beilstein J. Org. Chem., 12, 1314–1321 (2016) DOI:10.3762/bjoc.12.124.
2. “A Highly Active Biohybrid Catalyst for Olefin Metathesis in Water: Impact of a Hydrophobic Cavity in a β-Barrel Protein”
Daniel F. Sauer, Tomoki Himiyama, Kengo Tachikawa, Kazuki Fukumoto, Akira Onoda, Eiichi Mizohata, Tsuyoshi Inoue, Marco Bocola, Ulrich Schwaneberg, Takashi Hayashi,* and Jun Okuda*
ACS Catal., 5, 7519–7522 (2015). DOI: 10.1021/acscatal.5b01792.
3. “A Rhodium Complex-linked Hybrid Biocatalyst: Stereo-controlled Phenylacetylene Polymerization within an Engineered Protein Cavity”
Kazuki Fukumoto, Akira Onoda, Eiichi Mizohata, Marco Bocola, Tsuyoshi Inoue, Ulrich Schwaneberg, and Takashi Hayashi*
ChemCatChem, 6, 1229–1235 (2014). Front Cover. DOI: 10.1002/cctc.201301055.
4. “A Rhodium Complex-Linked ß-Barrel Protein as a Hybrid Biocatalyst for Phenylacetylene Polymerization”
Akira Onoda, Kazuki Fukumoto, Marcus Arlt, Marco Bocola, Ulrich Schwaneberg, and Takashi Hayashi*
Chem. Commun., 48, 9756–9758 (2012). DOI: 10.1039/C2CC35165J
5. “A Whole Cell E. coli Display Platform for Artificial Metalloenzymes: Poly(phenylacetylene) Production with a Rhodium–Nitrobindin Metalloprotein”
Alexander R. Grimm, Daniel F. Sauer, Tino Polen, Leilei Zhu, Takashi Hayashi, Jun Okuda, and Ulrich Schwaneberg*
ACS Catal., 8, 2611–2614 (2018), DOI: 10.1021/acscatal.7b04369.
6. ”Cavity Size Engineering of a β-Barrel Protein Generates Efficient Biohybrid Catalysts for Olefin Metathesis”
Alexander R. Grimm, Daniel F. Sauer, Mehdi D. Davari, Leilei Zhu, Marco Bocola, Shunsuke Kato, Akira Onoda, Takashi Hayashi, Jun Okuda*, and Ulrich Schwaneberg*
ACS Catal., 8, 3358–3364 (2018), DOI: 10.1021/acscatal.7b03652.
7. ”Incorporation of a Cp*Rh(III)-dithiophosphate Cofactor with Latent Activity into a Protein Scaffold Generates a Biohybrid Catalyst Promoting C(sp2)–H Bond Functionalization”
Shunsuke Kato, Akira Onoda*, Alexander R. Grimm, Kengo Tachikawa, Ulrich Schwaneberg, and Takashi Hayashi*
Inorg. Chem., 59, 14457–14463 (2020), DOI: 10.1021/acs.inorgchem.0c02245.
8. ”Directed Evolution of a Cp*RhIII‐Linked Biohybrid Catalyst Based on a Screening Platform with Affinity Purification”
Shunsuke Kato, Akira Onoda,* Naomasa Taniguchi, Ulrich Schwaneberg, and Takashi Hayashi*
ChemBioChem, 22, 679–685 (2021), DOI: 10.1002/cbic.202000681.
9. ”Construction of a whole-cell biohybrid catalyst using a Cp*Rh(III)-dithiophosphate complex as a precursor of a metal cofactor”
Shunsuke Kato, Akira Onoda,* Alexander R. Grimm, Ulrich Schwaneberg, and Takashi Hayashi*
J. Inorg. Biochem., 216, 111352 (2021), DOI: 10.1016/j.jinorgbio.2020.111352.
10. ”Evolutionary Engineering of a Cp*Rh(III) Complex-Linked Artificial Metalloenzyme with a Chimeric β-Barrel Protein Scaffold”
Shunsuke Kato, Akira Onoda*, Ulrich Schwaneberg, Takashi Hayashi*
J. Am. Chem. Soc., 145, 8285-8290 (2023), DOI: 10.1021/jacs.3c00581.
留学実績:
1. 2017.9 – 2017.12 加藤俊介(当時M2)
2. 2011.7 – 2012.10 福本和貴(当時 D1)